The predictive value of respiratory function tests for non-invasive ventilation in amyotrophic lateral sclerosis
نویسندگان
چکیده
منابع مشابه
The predictive value of respiratory function tests for non-invasive ventilation in amyotrophic lateral sclerosis
BACKGROUND Non-invasive ventilation (NIV) improves survival and quality of life in amyotrophic lateral sclerosis (ALS) patients. The timing of referral to a home ventilation service (HVS), which is in part based on respiratory function tests, has shown room for improvement. It is currently unknown which respiratory function test predicts an appropriate timing of the initiation of NIV. METHODS...
متن کاملRespiratory muscle function in amyotrophic lateral sclerosis.
Few data exist concerning expiratory muscle function in amyotrophic lateral sclerosis (ALS). We studied 26 patients with ALS (16 with respiratory symptoms and 10 without) and measured the maximal static expiratory mouth pressure (MEP), the gastric pressure during a maximal cough (Cough Pga), and the gastric pressure after magnetic stimulation of the lower thoracic nerve roots (Tw Pga). These me...
متن کاملPredicting the Need for Non-Invasive Ventilation in Patients with Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis (als) is a devastating neurodegenerative disease causing motor impairment. It is the third in the ranking of incidence of neurodegenerative diseases, has no cure, and its survival time after diagnosis is very limited. Since most patients die from respiratory failure, predicting the onset of hypoventilation is of major importance to prolong survival and improve the ...
متن کاملAssessment of pulmonary function in amyotrophic lateral sclerosis: when can polygraphy help evaluate the need for non-invasive ventilation?
BACKGROUND Non-invasive positive-pressure ventilation (NPPV) is an established, effective, long-term treatment for patients with amyotrophic lateral sclerosis (ALS), but the correct indicators for the establishment of NPPV have not been defined. METHODS In this retrospective study, records (spirometry, nocturnal polygraphy, nocturnal blood gases) of 131 patients with ALS were reviewed in orde...
متن کاملIs the effect of non-invasive ventilation on survival in amyotrophic lateral sclerosis age-dependent?
BACKGROUND Hypoventilation due to respiratory muscle atrophy is the most common cause of death as a result of amyotrophic lateral sclerosis (ALS). Patients aged over 65 years and presenting bulbar symptoms are likely to have a poorer prognosis. The aim of the study was to assess the possible impact of age and treatment with non-invasive ventilation (NIV) on survival in ALS. Based on evidence fr...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Respiratory Research
سال: 2017
ISSN: 1465-993X
DOI: 10.1186/s12931-017-0624-8